Roger Federer, who beat Murray in the 2015 final at Wimbledon, is seeded third and Stan Wawrinka fourth.
But it’s an opportunity and that can also play tricks on some players’ minds.
Novak Djokovic and Serena Williams are the top seeds for Wimbledon singles play in 2016.
Entering Friday's morning draw, Andy Murray was the second seed and would not meet Djokovic at the All-England Club until the final.
It would be their eighth Grand Slam championship singles match.
Djokovic won the first two legs of the tennis Grand Slam and hits London as the first men's player since 1992 -- Jim Courier -- to enter Wimbledon with successive singles slam titles.